Metal Chemistry of Alzheimer’s Disease The metal ion hypothesis proposed that AD was associated with dyshomeostasis of metal ions, most particularly…
Alzheimers…!Was a problem, is a problem, …, would not be a PROBLEM.Another antibody lecanemab-irmb (by Eisai and Biogen), following donanemab…
Machine learning and AI based methods are rapidly shaping the future technologies. Computer aided drug design is no exception. This…
Rigorous absolute binding free energy (ABFE) calculations are increasingly gaining attention as an important component of modern virtual screening (VS)…
Pan-assay interference compounds, or PAINS, are a specific group of compounds with defined structures that fall into several classes. However,…
The FDA approved the cMet/ALK dual inhibitor Crizotinib in 2011. In human cancers, the overexpression of the c-Met protein has…
In the field of drug discovery, ML can be used to analyze large amounts of data from various sources, including…
