• Computational siRNA Design

Computational siRNA Design


siRNAs represent the next-generation molecular therapeutics capable of treating a variety of diseases through gene silencing. siRNAs can play a central role in inhibiting the expression of disease-causing genes by hybridization and subsequent inactivation of the complementary target mRNAs through the RNA interference (RNAi) pathway. We employ computational tools to design experimentally testable specific siRNA sequences for different targets.